prof. RNDr. Jan Vondráček, Ph.D.

2024

• Transcriptional and phenotypical alterations associated with a gradual benzo[a]pyrene-induced transition of human bronchial epithelial cells into mesenchymal-like cells

  HYZDALOVA Martina PROCHÁZKOVÁ Jiřina STRAKOVA Nicol PENCIKOVA Katerina STRAPÁČOVÁ Simona SLOVÁČKOVÁ Jana KAJABOVA Simona LIBALOVA Helena TOPINKA Jan KABÁTKOVÁ Markéta VONDRÁČEK Jan MOLLERUP Steen MACHALA Miroslav

  Article in Periodical

  Environmental Toxicology and Pharmacology, year: 2024, volume: 107, DOI

2023

• Aryl hydrocarbon receptor (AhR) and pregnane X receptor (PXR) play both distinct and common roles in the regulation of colon homeostasis and intestinal carcinogenesis

  VÁZQUEZ GÓMEZ Gerardo PETRÁŠ Jiří DVOŘÁK Zdeněk VONDRÁČEK Jan

  Article in Periodical

  Biochemical Pharmacology, year: 2023, volume: 216, edition: October 2023, DOI

• Benzo[b]naphtho[d]thiophenes and naphthylbenzo[b]thiophenes: Their aryl hydrocarbon receptor-mediated activities and environmental presence

  MARVANOVÁ Soňa PĚNČÍKOVÁ Kateřina PÁLKOVÁ Lenka CIGANEK Miroslav PETRÁŠ Jiří LNĚNIČKOVÁ Anna VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  Science of The Total Environment, year: 2023, volume: 879, edition: June 2023, DOI

• DISRUPTION OF PROTEIN SYNTHESIS INDUCED BY PAHS IN HUMAN HEPATIC CELL LINES

  PETRÁŠ Jiří LNĚNIČKOVÁ Anna KARASOVÁ Martina VONDRÁČEK Jan

  Conference abstract

  Year: 2023, type: Conference abstract

• Effects of benzo[k]fluoranthene, a potent AhR ligand, on proteosynthesis and glucose metabolic regulators/effectors in liver cell models

  PETRÁŠ Jiří KARASOVÁ Martina LNĚNIČKOVÁ Anna MACHALA Miroslav ŠIMEČKOVÁ Pavlína VONDRÁČEK Jan

  Appeared in Conference without Proceedings

  Year: 2023, type: Appeared in Conference without Proceedings

• Immortalized human MIHA hepatocyte cell line as a model for analysis of activation of nuclear receptors linked with disruption of lipid metabolism

  PETRÁŠ Jiří KABÁTKOVÁ Markéta RAPTOVÁ Petra LNĚNIČKOVÁ Anna VONDRÁČEK Jan

  Conference abstract

  Year: 2023, type: Conference abstract

• Switching on/off aryl hydrocarbon receptor and pregnane X receptor activities by chemically modified tryptamines

  SLÁDEKOVÁ Lucia ZGARBOVÁ Eliška VRZAL Radim VANDA David SOURAL Miroslav JAKUBCOVÁ Klára VÁZQUEZ-GÓMEZ Gerardo VONDRÁČEK Jan DVOŘÁK Zdeněk

  Article in Periodical

  Toxicology Letters, year: 2023, volume: vol. 387

2021

• A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype

  HYZDALOVA Martina PROCHÁZKOVÁ Jiřina STRAPACOVA Simona SVRZKOVA Lucie VACEK Ondřej FEDR Radek ANDRYSÍK Zdeněk HRUBA Eva LIBALOVA Helena KLEMA Jiri TOPINKA Jan MASEK Josef SOUČEK Karel VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  Chemosphere, year: 2021, volume: 263, edition: January 2021, DOI

• Complex Alterations of Fatty Acid Metabolism and Phospholipidome Uncovered in Isolated Colon Cancer Epithelial Cells

  HOFMANOVÁ Jiřina SLAVIK Josef CIGANEK Miroslav OVESNÁ Petra TYLICHOVA Zuzana KARASOVÁ Martina ZAPLETAL Ondrej STRAKOVA Nicol PROCHAZKOVA Jirina BOUCHAL Jan KOLAR Zdenek EHRMANN Jiri LEVKOVA Monika HUSKOVA Zlatka SKALICKY Pavel KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  International Journal of Molecular Sciences, year: 2021, volume: 22, edition: 13, DOI

• Changes in Sphingolipid Profile of Benzo[a]pyrene-Transformed Human Bronchial Epithelial Cells Are Reflected in the Altered Composition of Sphingolipids in Their Exosomes

  MACHALA Miroslav SLAVIK Josef KOVAC Ondrej PROCHÁZKOVÁ Jiřina PENCIKOVA Katerina PARENICOVA Martina STRAKOVA Nicol KOTOUCEK Jan KULICH Pavel MOLLERUP Steen VONDRÁČEK Jan HYZDALOVA Martina

  Article in Periodical

  International Journal of Molecular Sciences, year: 2021, volume: 22, edition: 17, DOI